Agent-Based Simulation of a Tuberculosis Epidemic Parastu Kasaie, David W. Dowdy, W. David Kelton, Proceedings of the 2013 Winter Simulation Conference

We propose an epidemic agent-based simulation model for disease (TB) transmission dynamics study and to find out the role of various contact networks. Our model simulates the TB epidemic course across a single population and uses a hierarchical network of contacts in three levels, typical to the transmission of airborne diseases (Mossong et al. 2005). Parameters are chosen from the literature, and the model is calibrated to a setting of high TB incidence. We use our model to study the transmission dynamics at an individual level with regard to the timing and distribution of secondary infections from a single source. The average time for disease diffusion to reach 50% of infections at an individual level is estimated, and the timing patterns are compared among different networks. We perform sensitivity analysis of results with regard to multiple parameter values, and discuss the implications for TB control policy.
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West Nile Virus System Dynamics Investigation In Dallas County, TX Mohammad F. Obeid, John Shull, Proceedings of the 2013 Winter Simulation Conference

After its first introduction in 1999, West Nile Virus (WNV) has spread very widely along the east coasts of the United States before appearing in Texas where 1792 cases were reported of which 82 were fatal in 2012. The interesting patterns and behavior of the virus and its amplified impact on the county of Dallas drove this work. This paper encompasses a thorough development of a systems dynamics simulation model of virus's infectious behavior and dynamics in Dallas County, TX utilizing historical data collected and the aid of suitable software packages.
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A Modular Simulation Model For Assessing Interventions For Abdominal Aortic Aneurysms Christoph Urach, Günther Zauner, Gottfried Endel, Ingrid Wilbacher, Felix Breitenecker, Proceedings of the 2013 Winter Simulation Conference

This paper discusses the development of an individual based simulation of interventions for better treatment of patients with abdominal aortic aneurysms (AAA). The interdisciplinary subject required collaboration of medical doctors, Health Technology Assessment (HTA) experts and modelers.
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Prospective Healthcare Decision-Making By Combined System Dynamics, Discrete-Event And Agent-Based Simulation Anatoli Djanatliev, Reinhard German, Proceedings of the 2013 Winter Simulation Conference

Prospective Health Technology Assessment allows early decision making for innovative health care technologies. In our recent publications a hybrid simulation approach with System Dynamics and Agent-Based Modeling has been presented. This paper presents a mechanism to generate agents dynamically from SD models and extends the previously presented hybrid approach by process-oriented Discrete Event Simulation for hospital modeling.
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Large Scale Healthcare Modeling by Hybrid Simulation Techniques using AnyLogic Anatoli Djanatliev and Reinhard German, Computer Networks and Communication Systems Department of Computer Science 7. Proceedings of the 6th International ICST Conference on Simulation Tools and Techniques

This paper describes a methodical and practical approach of hybrid model creation using the simulation tool AnyLogic. We focus on general modeling aspects and on advanced techniques using a Level-Based Architecture that help to develop large scale hybrid simulation models. An implementation of a stroke therapy use-case and its simulation results will be discussed. Finally, some practical ideas for validation will be outlined, as we experienced during the stroke use-case development.
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Simulazione discreta con il software AnyLogic. Caratteristiche generali e applicazione ad unostudio oculistico Mattia Munaro, the University of Padua, Faculty of Engineering, 2009-2010

AnyLogic è un ambiente di modellazione virtuale di sistemi discreti, continui ed ibridi. Con questo strumento è possibile creare prototipi di sistemi durante le fasi di studio, progettazione o sviluppo, attraverso cui esplorare aspetti e dettagli della progettazione o della implementazione dei relativi sistemi in modo semplice e privo di rischi
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A simulation modeling approach for improving oral health outcomes of older adults Michael J. Widener, University at Buffalo

This interdisciplinary research focuses on improving the oral health of older adults as a means of enhancing their overall wellbeing and quality of life. Periodontal disease is a risk factor for other chronic illnesses, notably diabetes and cardiovascular disease. In order to identify policies that improve oral health for older adults, a dynamic modeling approach that considers community and individual level factors is utilized.
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VirSim - a Model to Support Pandemic Policy Making Tobias Fasth, Marcus Ihlar, Lisa Brouwers. PLoS Currents: Influenza. September 2010.

A simulation model called VirSim was developed to aid policy making in Sweden. The model simulates the spread of pandemic influenza, using real population data on a national and regional level. Swedish authorities wanted a model that was both quick to run and to implement as a complement to the existing model MicroSim.
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Toward Simulation-Based Real-Time Decision-Support Systems for Emergency Departments Yariv N. Marmor, Segev Wasserkrug, Avraham Shtub. 2009 Winter Simulation Conference (WSC’09), December 13-16, Austin, TX, USA

Emergency Departments (EDs) require advanced support systems for monitoring and controlling their processes: clinical, operational, and financial. A prerequisite for such a system is comprehensive operational information (e.g. queueing times, busy resources,…), reliably portraying and predicting ED status as it evolves in time. To this end, simulation comes to the rescue, through a two-step procedure that is hereby proposed for supporting real-time ED control.
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A Modern Simulation Approach for Pharmaceutical Portfolio Management Kirk Solo and Mark Paich. International Conference on Health Sciences Simulation (ICHSS'04), January 18 - 21, 2004, San Diego, California, USA

By creating an integrated simulation environment that models the underlying structure of a pharmaceutical enterprise portfolio it becomes possible to identify the optimal longitudinal allocation of finite resources across the constellation of available investment opportunities. The implementation of a hybrid approach that integrates multiple modeling techniques and analytic disciplines allows for a comprehensive environment that captures the underlying dynamics that drive observed market behavior. The implementation of an object oriented model structure constrains the models complexity by supporting dynamic re-use of both structure and logic.
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